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A Comparative Laboratory Study on the Effectiveness of Aloe vera Extracts and Nystatin in Inhibiting the Growth of Candida albicans.
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چکیده: (224 مشاهده) |
Background: Candida albicans is the most prevalent cause of oral fungal infections. This study aimed to compare the effectiveness of different dilutions of Aloe vera extracts (water and alcoholic )in inhibiting the growth of oral Candida albicans compared to nystatin.
Materials & Methods: This study was an experimental and laboratory investigation of a common strain of Candida albicans species in Iran. Different dilutions (1.56, 3.12, 6.25, 12.5, 25, 50, 100, and 200 mg/ml) of alcoholic and water extracts of Aloe vera and nystatin were prepared. The study measured the diameter of the inhibition zone of Candida albicans and assessed the impact of nystatin or Aloe vera extracts on this parameter. All data were analyzed using two-way ANOVA, Post hoc Bonferroni test, and t-test (α= 0.05).
Results: Both water and alcoholic extracts of Aloe vera at a concentration of 200 mg/ml produced a larger non-growth halo. Water extracts were more effective than alcoholic extracts at certain dilutions (p<0.001). Both water and alcoholic Aloe vera extract dilutions showed better results than nystatin (p<0.001).
Conclusion: The antifungal efficacy of water-soluble Aloe vera was significantly superior to alcoholic extracts and nystatin.
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نوع مطالعه: پژوهشي |
موضوع مقاله:
بیماری های دهان
دریافت: 1403/3/17 | پذیرش: 1403/11/7 | انتشار: 1403/12/15
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