[Home ] [Archive]    
:: Main :: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
Main Menu
Home::
Journal Information::
About the Journal
Editorial Board
Aims& Scopes
Journal News
publication ethics::
Abstracting and Indexing::
Articles archive::
All Issues
Current Issue
For Authors::
Call for Papers
Submission Instruction
Submission Form
For Reviewers::
Reviewers Section
Registration::
Registration Information
Registration Form
Contact us::
Contact Information
Contact us
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..

Citation Indices from GS

AllSince 2020
Citations88
h-index11
i10-index00
..
:: Volume 3, Issue 2 (5-2025) ::
cofs 2025, 3(2): 1-5 Back to browse issues page
Evaluation of Factors Associated with the Onset or Aggravation of Oral Lichenoid Reactions in Isfahan City of Iran
Zahra Faraji , Amir Mansour Shirani * , Nazanin Rezaei Mirghayed
Department of Oral Medicine, Faculty of Dentistry, Isf.C, Islamic Azad University, Isfahan, Iran
Abstract:   (223 Views)

Background: Lichenoid reactions include a group of lesions with different etiology but with common clinical and histological appearance. This study aimed to determine the prevalence of factors associated with oral lichenoid reactions, including dietary influences. This is the first study to evaluate these factors collectively.
Materials and methods: In this descriptive-analytic study, 73 oral lichenoid reaction patients’ files that were confirmed by biopsy and had complete recorded data in patients referred to IAU University and some oral medicine offices in Isfahan city were assessed for predisposing or aggravating factors. The data were analyzed by Chi-squared test and analysis of variance by SPSS 20 (α=0.05)
Results: There were significant relationships between stress (p=0.01), some kinds of toothpaste (Pooneh, Sensodyne) (p=0.04), metal (amalgam filling, PFM crowns and bridge, chrome cobalt dentures) (p<0.001), some drugs (for hypertension, diabetes, hypothyroidism) (p<0.001), some foods (date and spices) (p=0.04) with oral lichenoid reactions.
Conclusion: Amalgam filling, PFM crown and bridge, chrome cobalt dentures and 3 groups of drugs were the most related factors to oral lichenoid reactions but stress, some toothpastes and foods were also related.
Full-Text [PDF 402 kb]   (80 Downloads)    
Type of Study: Research | Subject: Oral Medicine
Received: 2024/05/12 | Accepted: 2025/01/2 | Published: 2025/05/20
References
1. Glick M, Greenberg MS, Lockhart PB, Challacombe SJ. Burket's Oral Medicine. 13th ed. Hoboken: Wiley-Blackwell, 2021.p:85-138. [DOI:10.1002/9781119597797]
2. Agha‐Hosseini F, Mirzaii‐Dizgah I, Farmanbar N, Abdollahi M. Oxidative stress status and DNA damage in saliva of human subjects with oral lichen planus and oral squamous cell carcinoma. J Oral Pathol Med. 2012;41(10):736-740. [DOI:10.1111/j.1600-0714.2012.01172.x] [PMID]
3. Sugerman PB, Savage NW, Walsh LJ, Zhao ZZ, Zhou XJ, Khan A, et al. The pathogenesis of oral lichen planus. Crit Rev Oral Biol Med. 2002;13(4):350-365. [DOI:10.1177/154411130201300405] [PMID]
4. van der Waal I. Oral lichen planus and oral lichenoid lesions; a critical appraisal with emphasis on the diagnostic aspects. Med Oral Patol Oral Cir Bucal. 2009;14(7):E310-E314.
5. Gupta S, Jawanda MK. Oral lichen planus: An update on etiology, pathogenesis, clinical presentation, diagnosis and management. Indian J Dermatol. 2015;60(3):222-229. [DOI:10.4103/0019-5154.156315] [PMID] []
6. Scully C, Carrozzo M. Oral mucosal disease: Lichen planus. Br J Oral Maxillofac Surg. 2008;46(1):15-21 [DOI:10.1016/j.bjoms.2007.07.199] [PMID]
7. Ismail SB, Kumar SK, Zain RB. Oral lichen planus and lichenoid reactions: etiopathogenesis, diagnosis, management and malignant transformation. J Oral Sci. 2007;49(2):89-106. [DOI:10.2334/josnusd.49.89] [PMID]
8. Bokor-Bratić M, Pićurić I. The prevalence of precancerous oral lesions: Oral lichen planus. Archive of Oncology. 2001;9(2):107-9.
9. Shirani AM, Razavi SM, Khazaei S, Khaleghi MA, Haerian A. Evaluation of oral lichen planus frequency in patients referred to the Oral Pathology Department of Isfahan School of Dentistry during the last two decades. Journal of Isfahan Dental School 2010;6(4):272-277
10. Pakfetrat A, Basir Shabestari S, Falaki F. Five year clinical and epidemiologic findings of oral lichen planus patients referred to oral medicine department of Mashhad dental school-Iran. Journal of mashhad dental school. 2008;32(3):195-8.
11. Esmaeili N, Barzegari M, Rezaei M. Clinical manifestations of Lichen Planus: A report of 120 cases. Iranian Journal of Dermatology, 2005; 8(2): 110-114.
12. Khalili M, Shojaee M. A retrospective study of oral lichen planus in oral pathology department, Tehran University of Medical Sciences (1968-2002). J Dent Med-tums 2006; 19 (3) :45-52
13. Mathew AL, Pai KM, Sholapurkar AA, Vengal M. The prevalence of oral mucosal lesions in patients visiting a dental school in Southern India. Indian J Dent Res. 2008;19(2):99-103 [DOI:10.4103/0970-9290.40461] [PMID]
14. Sandhu SV, Sandhu JS, Bansal H, Dua V. Oral lichen planus and stress: An appraisal. Contemp Clin Dent. 2014;5(3):352-356. [DOI:10.4103/0976-237X.137946] [PMID] []
15. Ivanovski K, Nakova M, Warburton G, Pesevska S, Filipovska A, Nares S, et al. Psychological profile in oral lichen planus. J Clin Periodontol. 2005;32(10):1034-1040 [DOI:10.1111/j.1600-051X.2005.00829.x] [PMID]
16. Ebrahimi H, Pourshahidi S, Andisheh Tadbir A. Evaluation of the relationship between oral lichen planus and stress. Journal of Dentistry. 2011;12(1):43-7.
17. Kaomongkolgit R. Oral lichenoid drug reaction associated with antihypertensive and hypoglycemic drugs. J Drugs Dermatol. 2010;9(1):73-75.
18. Guijarro Guijarro B, López Sánchez AF. Lichenoid reaction caused by Clopidogrel, a new anti-platelet drug. Med Oral. 2003;8(1):33-37.
19. Scully C. Oral and maxillofacial medicine: the basis of diagnosis and treatment. 4th ed. Elsevier Health Sciences; 2023,94-102
20. Mårell L, Tillberg A, Widman L, Bergdahl J, Berglund A. Regression of oral lichenoid lesions after replacement of dental restorations. J Oral Rehabil. 2014;41(5):381-391 [DOI:10.1111/joor.12151] [PMID]
21. Montebugnoli L, Venturi M, Gissi DB, Cervellati F. Clinical and histologic healing of lichenoid oral lesions following amalgam removal: a prospective study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;113(6):766-772. [DOI:10.1016/j.oooo.2011.12.007] [PMID]
22. Grossman S, Garcia BG, Soares I, Monteiro L, Mesquita R. Amalgam-associated oral lichenoid reaction: case report and management. Gen Dent. 2008;56(2):e9-e11
23. Serrano-Sánchez P, Bagán JV, Jiménez-Soriano, Sarrión G. Drug-induced oral lichenoid reactions: a literature review. J Clin Exp Dent. 2010;2(2):e71-5 [DOI:10.4317/jced.2.e71]
24. Scully C, Beyli M, Ferreiro MC, Ficarra G, Gill Y, Griffiths M, et al. Update on oral lichen planus: etiopathogenesis and management. Critical Reviews in Oral Biology & Medicine. 1998;9(1):86-122. [DOI:10.1177/10454411980090010501] [PMID]
25. Yildirim B, Sengüven B, Demir C. Prevalence of herpes simplex, Epstein Barr and human papilloma viruses in oral lichen planus. Med Oral Patol Oral Cir Bucal.20111;16(2):e170-4 [DOI:10.4317/medoral.16.e170] [PMID]
26. Michele G, Carlo L, Mario MC, Giovanni L, Pasquale M, Alessandra M. Hepatitis C virus chronic infection and oral lichen planus: an Italian case-control study. European journal of gastroenterology & hepatology. 2007;19(8):647-52. [DOI:10.1097/MEG.0b013e32821f6134] [PMID]
27. Garg VK, Karki B, Agrawal S, Agarwalla A, Gupta R. A study from Nepal showing no correlation between lichen planus and hepatitis B and C viruses. The Journal of Dermatology. 2002;29(7):411-3. [DOI:10.1111/j.1346-8138.2002.tb00295.x] [PMID]
28. Birkenfeld S, Dreiher J, Weitzman D, Cohen AD. A study on the association with hepatitis B and hepatitis C in 1557 patients with lichen planus J Eur Acad Dermatol Veneroel.2011;25(4):436-40. [DOI:10.1111/j.1468-3083.2010.03809.x] [PMID]
29. Adami GA, C F Yeung A, Stucki G, Kolokythas A, Sroussi HY, Cabay RJ, Kuzin I, Schwartz J. Gene expression based evidence of innate immune response activation in the epithelium with oral lichen planus. Arch Oral Biol 2014 ;59(3):354-61 [DOI:10.1016/j.archoralbio.2013.12.010] [PMID] []
30. Pakfetrat A, Javadzadeh-Bolouri A, Basir-Shabestari S, Falaki F. Oral Lichen Planus: a retrospective study of 420 Iranian patients. Med Oral Patol Oral Cir Bucal. 2009;14(7):E315-E318.
31. Kakoei S, Torabi M, Rad M, Karbasi N, Mafi S. Retrospective Study of Oral Lichen Planus and Oral Lichenoid Lesions: Clinical Profile and Malignant Transformation. J Dent (Shiraz). 2022;23(4):452-458
32. Elenbaas A, Enciso R, Al-Eryani K. Oral lichen planus: a review of clinical features, etiologies, and treatment. Dentistry Review. 2022; 2(1):10000 [DOI:10.1016/j.dentre.2021.100007]
Add your comments about this article
Your username or Email:

CAPTCHA

XML     Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Faraji Z, Shirani A M, Rezaei Mirghayed N. Evaluation of Factors Associated with the Onset or Aggravation of Oral Lichenoid Reactions in Isfahan City of Iran. cofs 2025; 3 (2) :1-5
URL: http://cofs.khuisf.ac.ir/article-1-82-en.html
Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 3, Issue 2 (5-2025) Back to browse issues page
Contemporary Orofacial Science Contemporary Orofacial Science
Persian site map - English site map - Created in 0.05 seconds with 39 queries by YEKTAWEB 4714