fa آسیب شناسی دهان و دندان Oral & Maxillofacial Pathology پژوهشي Research <div style="text-align: justify;"><span style="font-size:12px;"><span style="font-family:Tahoma;"><span style="line-height:200%"><b>Background:</b> Fibrotic changes of Oral Lichen Planus (OLP) is a possible underlying cause of trismus in OLP patients and might have a role in malignant progression of OLP as well. Research relates the fibrotic change in tissue to myofibroblasts. Thus, this study aimed to review the published articles regarding the role of myofibroblasts in fibrosis of OLP lesional tissues.</span><br> <span style="line-height:200%"><b>Methods:</b> PubMed Central search engine and Google Scholar were used to gather information from full-text articles published between 2000 and 2025 pertaining to &ldquo;myofibroblast and oral lichen planus and fibrosis.&quot; The most relevant articles were selected and studied.</span><br> <span style="line-height:200%"><b>Conclusion:</b> Based on information gathered from previous studies, it can be concluded that myofibroblasts play role in the fibrotic changes associated with oral lichen planus. But further studies are required in order to make precise conclusions. </span></span></span></div> 0 0 http://cofs.khuisf.ac.ir/browse.php?a_code=A-10-1-85&slc_lang=fa&sid=1 Bahareh Bagheri Todeshki 10031947532846001495 10031947532846001495 No Department of Oral and Maxillofacial Medicine, Faculty of Dentistry, Isf.C., Islamic Azad University, Isfahan, Iran Fatemeh Jabbarpour 10031947532846001496 10031947532846001496 No Department of Periodontics, Faculty of Dentistry, Isf.C., Islamic Azad University, Isfahan, Iran Roya Yahyaabadi 10031947532846001497 10031947532846001497 No Department of Oral and Maxillofacial Pathology. Faculty of Dentistry, Shahrekord University of Medical Sciences, Shahrekord, Iran Atousa Aminzadeh 10031947532846001498 10031947532846001498 Yes Department of Oral Maxillofacial Pathology, Faculty of Dentistry, Isf.C, Islamic Azad University, Isfahan, Iran Ava Behrouziyan 10031947532846001499 10031947532846001499 No Faculty of Dentistry, Isf.C, Islamic Azad University, Isfahan, Iran Sayed Majid Askari 10031947532846001500 10031947532846001500 No School of medicine , Islamic Azad University, Zahedan , Iran